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Essential Organic Chemistry

Title
Essential Organic Chemistry
Semester
E2024
Master programme in
Chemical Biology
Type of activity

Course

Teaching language
English
Study regulation

Read about the Master Programme and find the Study Regulations at ruc.dk

Læs mere om uddannelsen og find din studieordning på ruc.dk

REGISTRATION AND STUDY ADMINISTRATIVE
Registration

Sign up for study activities at stads selvbetjeningwithin the announced registration period, as you can see on the Studyadministration homepage.

When signing up for study activities, please be aware of potential conflicts between study activities or exam dates.

The planning of activities at Roskilde University is based on the recommended study programs which do not overlap. However, if you choose optional courses and/or study plans that goes beyond the recommended study programs, an overlap of lectures or exam dates may occur depending on which courses you choose.

Number of participants
ECTS
10
Responsible for the activity
William Goldring (goldring@ruc.dk)
Head of study
Frederik Diness (diness@ruc.dk)
Teachers
Study administration
INM Registration & Exams (inm-exams@ruc.dk)
Exam code(s)
U60042
ACADEMIC CONTENT
Overall objective

Organic chemistry plays an important, central role in our everyday life. From the synthesis of new medicines for health, or the construction of new materials and catalysts for industrial processes and energy production, to developing an understanding of how chemical and biological processes work, each area requires a strong foundation in and knowledge of organic chemistry.

The course will describe and illustrate the structure, properties and chemical reactions and reactivity of organic molecules, using a number of relevant examples systematically organised around functional group structures. Furthermore, a number of fundamental reaction mechanisms, such as substitution, elimination, addition and rearrangement processes, will be discussed and illustrated to develop a deeper understanding of these processes, and to help the student to account for reaction outcomes, product formation and selectivity. Finally, the application of organic chemistry, including the reactivity of the products resulting from the reactions that appear in this course, will be described in the context of multistep synthesis, together with new concepts and issues that arise in the design and implementation of such efforts.

Laboratory experiments will introduce the principles of organic synthesis and the identification of reaction products from experimental data, such as IR and NMR. The experiments will complement as well as add to the content of the lectures.

Detailed description of content

Aspects of the following topics will be discussed throughout the course:

Organic Reactions (Ch. 6) Alkenes and Alkynes (Ch. 7 and 8) Substitution & Elimination (Ch. 12) Alcohols and Ethers (Ch. 13) Aldehydes and Ketones (Ch. 14) Carboxylic Acid Derivatives (Ch. 15 and 16) Carbonyl alpha-Substitution (Ch. 17) Aromatic Compounds (Ch. 9) Amines & Heterocycles (Ch. 18)

Detailed Teaching Objectives and Learning Outcomes

After successful completion of the course the student will be able to demonstrate and apply:

Knowledge of:

  • nomenclature in organic chemistry.

  • structure, reactivity and properties of organic compounds.

  • organic reaction mechanisms.

  • factors governng organic chemistry reactions.

  • phenomena such as geometric isomerism, stereoisomerism, and tautomerism.

  • the role reagents play, and the possible products formed, in various organic chemistry reactions.

  • multistep synthesis route design.

Skills in:

  • solving unfamiliar problems through the application of skills and strategies in problem-solving and independent learning.

  • safe handling of organic compounds.

  • performing a chemical synthesis experiment according to a written procedure.

  • interpreting the results and outcome of experiments involving the construction of organic compounds.

  • interpreting the measurements of organic compounds.

Learning outcomes:

  • translate between the name and the structure of an organic compound.

  • use a reaction mechanism to account for the reaction of an organic compound based on its structure and the reagents involved.

  • describe and illustrate organic chemistry reaction mechanisms.

  • compare and contrast the structure, reactivity and properties of a group of organic molecules.

  • determine the outcome of a reaction and account for the product formed, and determine the reagents required to achieve a specific reaction outcome.

  • develop a synthetic plan to construct a target structure, a structure type, or to interconvert between structure types.

Course material and Reading list

Textbook:

J. McMurry, Organic Chemistry with Biological Applications, 3rd Ed., Cengage Learning, 2015. Chapters 6-9 and 12-18.

Other materials:

  • Powerpoint slides will be posted on Moodle during the course, prior to each lecture.

  • Problem sets will be posted on Moodle during the course, prior to each workshop.

  • A laboratory manual will be posted on Moodle by mid-September and detailed pre- and post-laboratory assignments will be posted on Moodle before and after each session.

Overall plan and expected work effort

10 ECTS corresponds to 270 hours of work

The work load for the student:

Contact time:

  • lectures and workshops 60 hours

  • laboratory sessions 16 hours

  • examination 4 hours

Study and preparation time:

  • reading and self-revision problems 60 hours,

  • theoretical problem preparation 45 hours,

  • laboratory and assignments 40 hours,

  • revision and exam preparation 45 hours.

Total 270 hours

Format
Evaluation and feedback

The course includes formative evaluation based on dialogue between the students and the teacher(s).

Students are expected to provide constructive critique, feedback and viewpoints during the course if it is needed for the course to have better quality. Every other year at the end of the course, there will also be an evaluation through a questionnaire in SurveyXact. The Study Board will handle all evaluations along with any comments from the course responsible teacher.

Furthermore, students can, in accordance with RUCs ‘feel free to state your views’ strategy through their representatives at the study board, send evaluations, comments or insights form the course to the study board during or after the course.

Programme

The course is organized around a combination of lectures (powerpoint, boardwork, and discussion), problem solving workshops and laboratory experiment sessions. See study.ruc.dk for a detailed course calendar, and the course page on Moodle for a schedule, course description, laboratory manual and other documents, together with lecture notes, problem solving questions and laboratory report assignments.

Each lecture section is followed by a problem solving workshop, organized according to the course schedule on Moodle. Students will find questions associated with a particular lecture section in separate files uploaded to the course Moodle page.

Students are expected to complete or attempt the problem solving questions associated with a particular workshop, before it takes place, and be prepared to present their solutions, in whole or in part, during the workshop.

Two reports must be completed for each laboratory experiment. One is a short pre-lab report due before the experiment session, and the other post-lab report must be completed before the following session.

ASSESSMENT
Overall learning outcomes

After successful completion of the course the student will be able to:

  • translate between nomenclature and structure of organic compounds

  • use a reaction mechanism to account for the reaction of an organic compound based on its structure and the reagents involved

  • solve unfamiliar problems through the application of skills and strategies in problem-solving and independent learning

  • safely handle organic compounds

  • perform a chemical synthesis experiment according to a written procedure

  • describe and illustrate organic chemistry reaction mechanisms

  • compare and contrast the structure, reactivity and properties of a group of organic molecules

  • determine the outcome of a reaction and account for the product formed

  • develop a synthetic plan to construct a structure type, or to interconvert between structure types

  • interpret measurements of organic compounds

  • interpret the results and outcome of experiments involving organic compounds.

Form of examination
Individual written invigilated exam

The duration of the exam is 4 hours.

Permitted support and preparation materials for the exam: Computer without internet access during the exam, pocket calculator, course material and own notes.


Assessment: 7-point grading scale.
Moderation: External examiner.
Form of Re-examination
Samme som ordinær eksamen / same form as ordinary exam
Type of examination in special cases
Examination and assessment criteria

Individual written invigilated exam based on a set of problem solving questions.

Assessment criteria/the student will be assessed on their ability to:

  • translate between the name and the structure of an organic compound.

  • compare and contrast the structure, reactivity and properties of a group of organic molecules.

  • use a reaction mechanism to account for the reaction of an organic compound based on its structure and the reagents involved.

  • determine the outcome of a reaction and account for the product formed.

  • determine the reagents required to achieve a specific reaction outcome.

  • develop a synthetic plan to construct a target structure, a structure type, or to interconvert between structure types.

-apply problem based skills, methods and strategies to solve unfamiliar problems

Exam code(s)
Exam code(s) : U60042
Last changed 05/04/2024

lecture list:

Show lessons for Subclass: 1 Find calendar (1) PDF for print (1)

Tuesday 03-09-2024 12:15 - 03-09-2024 14:00 in week 36
Essential Organic Chemistry (CB)

Wednesday 04-09-2024 08:15 - 04-09-2024 10:00 in week 36
Essential Organic Chemistry (CB)

Tuesday 10-09-2024 12:15 - 10-09-2024 14:00 in week 37
Essential Organic Chemistry (CB)

Friday 13-09-2024 10:15 - 13-09-2024 12:00 in week 37
Essential Organic Chemistry (CB)

Tuesday 17-09-2024 12:15 - 17-09-2024 14:00 in week 38
Essential Organic Chemistry (CB)

Friday 20-09-2024 10:15 - 20-09-2024 12:00 in week 38
Essential Organic Chemistry (CB)

Friday 20-09-2024 13:00 - 20-09-2024 18:00 in week 38
Essential Organic Chemistry - Flexible laboratory hours (CB)

Tuesday 24-09-2024 12:15 - 24-09-2024 14:00 in week 39
Essential Organic Chemistry (CB)

Friday 27-09-2024 10:15 - 27-09-2024 12:00 in week 39
Essential Organic Chemistry (CB)

Monday 30-09-2024 08:15 - 30-09-2024 10:00 in week 40
Essential Organic Chemistry (CB) - Note: Monday due to Preparatory Thesis Seminar

Friday 04-10-2024 10:15 - 04-10-2024 12:00 in week 40
Essential Organic Chemistry (CB)

Friday 04-10-2024 13:00 - 04-10-2024 18:00 in week 40
Essential Organic Chemistry - Flexible laboratory hours (CB)

Tuesday 08-10-2024 12:15 - 08-10-2024 14:00 in week 41
Essential Organic Chemistry (CB)

Friday 11-10-2024 10:15 - 11-10-2024 12:00 in week 41
Essential Organic Chemistry (CB)

Tuesday 22-10-2024 12:15 - 22-10-2024 14:00 in week 43
Essential Organic Chemistry (CB)

Wednesday 23-10-2024 08:15 - 23-10-2024 10:00 in week 43
Essential Organic Chemistry (CB)

Tuesday 29-10-2024 12:15 - 29-10-2024 14:00 in week 44
Essential Organic Chemistry (CB)

Friday 01-11-2024 10:15 - 01-11-2024 12:00 in week 44
Essential Organic Chemistry (CB)

Friday 01-11-2024 13:00 - 01-11-2024 18:00 in week 44
Essential Organic Chemistry - Flexible laboratory hours (CB)

Tuesday 05-11-2024 12:15 - 05-11-2024 14:00 in week 45
Essential Organic Chemistry (CB)

Friday 08-11-2024 10:15 - 08-11-2024 12:00 in week 45
Essential Organic Chemistry (CB)

Tuesday 12-11-2024 12:15 - 12-11-2024 14:00 in week 46
Essential Organic Chemistry (CB)

Friday 15-11-2024 10:15 - 15-11-2024 12:00 in week 46
Essential Organic Chemistry (CB)

Friday 15-11-2024 13:00 - 15-11-2024 18:00 in week 46
Essential Organic Chemistry - Flexible laboratory hours (CB)

Tuesday 19-11-2024 12:15 - 19-11-2024 14:00 in week 47
Essential Organic Chemistry (CB)

Friday 22-11-2024 10:15 - 22-11-2024 12:00 in week 47
Essential Organic Chemistry (CB)

Tuesday 26-11-2024 12:15 - 26-11-2024 14:00 in week 48
Essential Organic Chemistry (CB)

Friday 29-11-2024 10:15 - 29-11-2024 12:00 in week 48
Essential Organic Chemistry (CB)

Tuesday 03-12-2024 12:15 - 03-12-2024 14:00 in week 49
Essential Organic Chemistry (CB)

Friday 06-12-2024 10:15 - 06-12-2024 12:00 in week 49
Essential Organic Chemistry (CB)

Tuesday 10-12-2024 12:15 - 10-12-2024 14:00 in week 50
Essential Organic Chemistry (CB)

Friday 13-12-2024 10:15 - 13-12-2024 12:00 in week 50
Essential Organic Chemistry (CB)

Monday 13-01-2025 10:00 - 13-01-2025 14:00 in week 03
Essential Organic Chemistry - Exam (CB)

Wednesday 26-02-2025 12:30 - 26-02-2025 16:30 in week 09
Essential Organic Chemistry - Reexam (CB)