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Preparation and Testing of Biopharmaceuticals

Title
Preparation and Testing of Biopharmaceuticals
Semester
F2024
Master programme in
Chemical Biology / Molecular Health Science
Type of activity

Laboratory Course

Teaching language
English
Study regulation

Read about the Master Programme and find the Study Regulations at ruc.dk

Læs mere om uddannelsen og find din studieordning på ruc.dk

REGISTRATION AND STUDY ADMINISTRATIVE
Registration

Sign up for study activities at stads selvbetjening within the announced registration period, as you can see on the Studyadministration homepage.

When signing up for study activities, please be aware of potential conflicts between study activities or exam dates.

The planning of activities at Roskilde University is based on the recommended study programs which do not overlap. However, if you choose optional courses and/or study plans that goes beyond the recommended study programs, an overlap of lectures or exam dates may occur depending on which courses you choose.

Number of participants

The Master Programme/Institute reserves the right to cancel the course if fewer than 8 studentes are registered for the course.

ECTS
5
Responsible for the activity
Biljana Mojsoska (biljana@ruc.dk)
Håvard Jenssen (jenssen@ruc.dk)
Frederik Diness (diness@ruc.dk)
Head of study
Lotte Jelsbak (ljelsbak@ruc.dk)
Teachers
Study administration
INM Studieadministration (inm-studieadministration@ruc.dk)
Exam code(s)
U60588
ACADEMIC CONTENT
Overall objective

The purpose of the course is to teach the students synthesis approaches and make them able to choose suitable methods for peptide separation and analysis. Allow them to identify critical steps in peptide synthesis through analysis and/or develop interdisciplinary approach in drug development.

The course is a mixture of practical exercises and workshop/lecture confrontation.

Detailed description of content

Thematic session in peptide chemistry and drug design, will be covered with lectures, workshop and lab sessions.

Course material and Reading list

The curriculum will be made available on moodle

Overall plan and expected work effort
  • lectures 16 hrs

  • student presentations 8 hrs

  • practical exercises 24 hrs

  • report writing 40 hrs

  • preparation 46 hrs

  • Oral exam 0,25 hr

- total 135 hrs

The courses are each 5 ECTS and are case based. It is intended to have a total of 36 teaching hours and 1 extra slot each for introduction and preparation of the exam. So a total of 41 hours.

Format
Evaluation and feedback

The course includes formative evaluation based on dialogue between the students and the teacher(s).

Students are expected to provide constructive critique, feedback and viewpoints during the course if it is needed for the course to have better quality. Every other year at the end of the course, there will also be an evaluation through a questionnaire in SurveyXact. The Study Board will handle all evaluations along with any comments from the course responsible teacher.

Furthermore, students can, in accordance with RUCs ‘feel free to state your views’ strategy through their representatives at the study board, send evaluations, comments or insights form the course to the study board during or after the course.

Programme

The first lecture is a 2 hour introduction to the course and a brief overview of the different cases and how the course is structured and the exam is planned.

In week 2 the idea is to introduce a theoretical background of the first case and prepare the students for practical work that are related to the case in the coming 4 hours of practical work which could be a presentation of papers or start a lab. Therefore, we always start with a theoretical background (2 hours) and then we apply our knowledge in a hands on exercise (4 hours). We use two weeks for each case, and a total of 3 cases.

ASSESSMENT
Overall learning outcomes

After completing the course, the students will be able to:

  • describe classical peptide and peptidomimetic synthesis

  • demonstrate knowledge on the principles of peptide analytical and separation techniques

  • interpret peptides purification and analysis data

  • utilize software analysis to determine success of synthesis, identification and quantification of peptides.

Form of examination
The course is passed through active and satisfactory participation.

Active participation is defined as:
The student must participate in course related activities (e.g. workshops, seminars, field excursions, process study groups, working conferences, supervision groups, feedback sessions).

Satisfactory participation is defined as:
- e.g. oral presentations (individually or in a group), peer reviews, mini projects, test, planning of a course session .

Assessment: Pass/Fail.
Form of Re-examination
Samme som ordinær eksamen / same form as ordinary exam
Type of examination in special cases
Examination and assessment criteria

Active participation is defined as:

  • The student must participate in course related activities, eg. both lab and lecture sessions

Satisfactory participation is defined as:

  • oral presentations (individually or in a group) for fellow students, focusing on methodologies covered in the course in the form of mini projects, planning/preparations for the lab sessions.

  • Student pressentations will be reviewed by the fellow students, peer reviews, with critical and constructive comments.

  • approval of three lab reports

Assesment criteria: to which degree the student is able to:

  • describe classical peptide and peptidomimetic synthesis

  • demonstrate knowledge on the principles of peptide analytical and separation techniques

  • interpret peptides purification and analysis data

  • utilize software analysis to determine success of synthesis, identification and quantification of peptides.

Exam code(s)
Exam code(s) : U60588
Last changed 08/11/2023

lecture list:

Show lessons for Subclass: 1 Find calendar (1) PDF for print (1)

Monday 05-02-2024 10:15 - 05-02-2024 12:00 in week 06
Preparation and Testing of Biopharmaceuticals (CB)

Wednesday 07-02-2024 08:15 - 07-02-2024 12:00 in week 06
Preparation and Testing of Biopharmaceuticals (CB)

Monday 12-02-2024 14:15 - 12-02-2024 16:00 in week 07
Preparation and Testing of Biopharmaceuticals (CB)

Monday 19-02-2024 14:15 - 19-02-2024 16:00 in week 08
Preparation and Testing of Biopharmaceuticals (CB)

Wednesday 21-02-2024 08:15 - 21-02-2024 12:00 in week 08
Preparation and Testing of Biopharmaceuticals (CB)

Monday 26-02-2024 14:15 - 26-02-2024 16:00 in week 09
Preparation and Testing of Biopharmaceuticals (CB)

Wednesday 28-02-2024 08:15 - 28-02-2024 12:00 in week 09
Preparation and Testing of Biopharmaceuticals (CB)

Monday 04-03-2024 14:15 - 04-03-2024 16:00 in week 10
Preparation and Testing of Biopharmaceuticals (CB)

Wednesday 06-03-2024 08:15 - 06-03-2024 12:00 in week 10
Preparation and Testing of Biopharmaceuticals (CB)

Monday 11-03-2024 14:15 - 11-03-2024 16:00 in week 11
Preparation and Testing of Biopharmaceuticals (CB)

Wednesday 13-03-2024 08:15 - 13-03-2024 12:00 in week 11
Preparation and Testing of Biopharmaceuticals (CB)

Monday 18-03-2024 12:15 - 18-03-2024 14:00 in week 12
Preparation and Testing of Biopharmaceuticals (CB)

Wednesday 20-03-2024 10:15 - 20-03-2024 12:00 in week 12
Preparation and Testing of Biopharmaceuticals (CB)

Monday 25-03-2024 12:15 - 25-03-2024 14:00 in week 13
Preparation and Testing of Biopharmaceuticals (CB)

Wednesday 03-04-2024 08:15 - 03-04-2024 12:00 in week 14
Preparation and Testing of Biopharmaceuticals (CB)

Monday 08-04-2024 12:15 - 08-04-2024 14:00 in week 15
Preparation and Testing of Biopharmaceuticals (CB)

Wednesday 10-04-2024 08:15 - 10-04-2024 12:00 in week 15
Preparation and Testing of Biopharmaceuticals (CB)

Monday 15-04-2024 14:15 - 15-04-2024 16:00 in week 16
Preparation and Testing of Biopharmaceuticals (CB)

Wednesday 17-04-2024 08:15 - 17-04-2024 12:00 in week 16
Preparation and Testing of Biopharmaceuticals (CB)

Monday 22-04-2024 12:15 - 22-04-2024 14:00 in week 17
Preparation and Testing of Biopharmaceuticals (CB)

Wednesday 24-04-2024 08:15 - 24-04-2024 12:00 in week 17
Preparation and Testing of Biopharmaceuticals (CB)

Monday 29-04-2024 14:15 - 29-04-2024 16:00 in week 18
Preparation and Testing of Biopharmaceuticals (CB)

Wednesday 01-05-2024 08:15 - 01-05-2024 12:00 in week 18
Preparation and Testing of Biopharmaceuticals (CB)