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Biophysical Chemistry

Title
Biophysical Chemistry
Semester
F2023
Master programme in
Chemical Biology / Molecular Health Science / Physics and Scientific Modelling
Type of activity

Course

Teaching language
English
Study regulation

Read about the Master Programme and find the Study Regulations at ruc.dk

Læs mere om uddannelsen og find din studieordning på ruc.dk

REGISTRATION AND STUDY ADMINISTRATIVE
Registration

Sign up for study activities at stads selvbetjening within the announced registration period, as you can see on the Studyadministration homepage.

When signing up for study activities, please be aware of potential conflicts between study activities or exam dates.

The planning of activities at Roskilde University is based on the recommended study programs which do not overlap. However, if you choose optional courses and/or study plans that goes beyond the recommended study programs, an overlap of lectures or exam dates may occur depending on which courses you choose.

Number of participants

The Master Programme/Institute reserves the right to cancel the course if fewer than 8 studentes are registered for the course.

ECTS
5
Responsible for the activity
Jeppe Kari (jkari@ruc.dk)
Anders Malmendal (amalm@ruc.dk)
Head of study
Studieleder for Fysik (fys-sl@ruc.dk)
Teachers
Study administration
INM Registration & Exams (inm-exams@ruc.dk)
Exam code(s)
U60049
ACADEMIC CONTENT
Overall objective

The aim of this course is to give the student molecular-level understanding of the structure, stability, interactions and dynamics of proteins—basically “Why do proteins behave like they do and how can we interfere with it?”. The course will also introduce the principal methods used in modern protein science and provide practical experience in using some of these.

Detailed description of content

During the course there will be a series of lectures describing how and why macromolecules interact with themselves and other molecules. In parallel with this there will be a number of experimental sessions where we will use different types of biophysical characterisation and analyse the results.

Groups of students will write reports based on experiments carried out during the course.

Course material and Reading list

Pensum in this course are lecture notes and articles provided during the course.

Overall plan and expected work effort
  • Lectures: 21 hours

  • Preparation: 28 hours

  • Experimental sessions: 21 hours

  • Experimental evaluation and report writing: 40 hours

  • Exam: 25 hours

Total for this 5 ECTS course is 135 hours

Format
Evaluation and feedback

The course includes formative evaluation based on dialogue between the students and the teacher(s).

Students are expected to provide constructive critique, feedback and viewpoints during the course if it is needed for the course to have better quality. Every other year at the end of the course, there will also be an evaluation through a questionnaire in SurveyXact. The Study Board will handle all evaluations along with any comments from the course responsible teacher.

Furthermore, students can, in accordance with RUCs ‘feel free to state your views’ strategy through their representatives at the study board, send evaluations, comments or insights form the course to the study board during or after the course.

Programme

During the course there will be a series of lectures describing how and why macromolecules interact with themselves and other molecules.

In parallel with this there will be a number of experimental sessions where we will use different types of biophysical characterisation and analyse the results. Groups of students will write reports based on experiments carried out during the course.

ASSESSMENT
Overall learning outcomes

After completing the course the student will be able to:

  • account for the principal physico-chemical properties of proteins, such as structure, stability, interactions and dynamics and accounting for these properties in terms of molecular-level theroetical models

  • interpret experimental results from physico-chemical studies of proteins

  • apply physico-chemical concepts and models to solve problems involving proteins

  • carry out spectroscopic measurements on proteins

  • critically assess research literature in protein science, and effectively communicate with researchers in protein science.

Form of examination
Group portfolio and oral exam.

Permitted group size: 2-3 students. Examples of written products are exercise responses, talking points for presentations, written feedback, reflections, written assignments. The preparation of the products may be subject to time limits.

The character limit of the portfolio is:
For 2 students: 12,000-36,000 characters, including spaces.
For 3 students: 12,000-36,000 characters, including spaces.
The character limits include the cover, table of contents, bibliography, figures and other illustrations, but exclude any appendices.

Time allowed for exam including time used for assessment is for:
2 students: 45 minutes.
3 students: 60 minutes.

The assessment is individual and based on the student's individual performance.
The assessment is an overall assessment of the written product(s) and the subsequent oral examination..

Permitted support and preparation materials at the oral exam: Personal notes, own reports and assignments.

Assessment: Pass/Fail.
Moderation: Internal co-assessor.
Form of Re-examination
Samme som ordinær eksamen / same form as ordinary exam
Type of examination in special cases
Examination and assessment criteria

Groups of students will write reports based on experiments carried out during the course. The oral group exam will start with a presentation of the results described in the report.

The assessment criteria regarding the written part:

  • Account for the principal physico-chemical properties of proteins, such as structure, stability, interactions and dynamics and accounting for these properties in terms of molecular-level theroetical models.

  • Interpret experimental results from spectroscopic and other physico-chemical studies of proteins.

  • Apply physico-chemical concepts and models to solve problems involving proteins.

The assessment of the oral exam is based on the student’s ability to meet the criteria mentioned above and their ability to:

  • clearly present and communicate the scientific content of the reports

  • engage in a scientific dialoged and discussion with the assessors

Furthermore, whether the performance meets all formal requirements

The character limit of the portfolio is:

  • For 2 students: 12,000-36,000 characters, including spaces.

  • For 3 students: 12,000-36,000 characters, including spaces.

The character limits include the cover, table of contents, bibliography, figures and other illustrations, but exclude any appendices.

The assessment is an overall assessment

Exam code(s)
Exam code(s) : U60049
Last changed 06/03/2023

lecture list:

Show lessons for Subclass: 1 Find calendar (1) PDF for print (1)

Tuesday 14-02-2023 12:15 - 14-02-2023 16:00 in week 07
Biophysical Chemistry (CB)

Thursday 16-02-2023 12:15 - 16-02-2023 14:00 in week 07
Biophysical Chemistry (CB)

Tuesday 21-02-2023 12:15 - 21-02-2023 16:00 in week 08
Biophysical Chemistry (CB)

Thursday 23-02-2023 12:15 - 23-02-2023 14:00 in week 08
Biophysical Chemistry (CB)

Tuesday 28-02-2023 12:15 - 28-02-2023 16:00 in week 09
Biophysical Chemistry (CB)

Thursday 02-03-2023 12:15 - 02-03-2023 14:00 in week 09
Biophysical Chemistry (CB)

Tuesday 07-03-2023 12:15 - 07-03-2023 16:00 in week 10
Biophysical Chemistry (CB)

Thursday 09-03-2023 12:15 - 09-03-2023 14:00 in week 10
Biophysical Chemistry (CB)

Tuesday 14-03-2023 12:15 - 14-03-2023 16:00 in week 11
Biophysical Chemistry (CB)

Thursday 16-03-2023 12:15 - 16-03-2023 14:00 in week 11
Biophysical Chemistry (CB)

Tuesday 21-03-2023 12:15 - 21-03-2023 16:00 in week 12
Biophysical Chemistry (CB)

Thursday 23-03-2023 12:15 - 23-03-2023 14:00 in week 12
Biophysical Chemistry (CB)

Tuesday 28-03-2023 12:15 - 28-03-2023 16:00 in week 13
Biophysical Chemistry (CB)

Thursday 30-03-2023 12:15 - 30-03-2023 14:00 in week 13
Biophysical Chemistry (CB)

Thursday 20-04-2023 10:00 - 20-04-2023 10:00 in week 16
Biophysical Chemistry - Hand-in of portfolio (CB)

Tuesday 25-04-2023 08:15 - 25-04-2023 16:00 in week 17
Biophysical Chemistry - Exam (CB)

Friday 30-06-2023 10:00 - 30-06-2023 10:00 in week 26
Biophysical Chemistry - Hand-in of portfolio (reexam) (CB)

Monday 14-08-2023 08:15 - 14-08-2023 16:00 in week 33
Biophysical Chemistry - Reexam (CB)